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71 toradh

  1. SCIENCE|natural and applied sciences|life sciences
    córas léirithe géine Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    expression system | gene expression system
    en
    Sainmhíniú system consisting of a gene, normally encoded by DNA, and the molecular machinery required to transcribe the DNA into mRNA and translate the mRNA into protein using the reagents provided, specifically designed for the production of a gene product of choice - normally a protein although may also be RNA, such as tRNA or a ribozyme Tagairt "Gene Expression System, http://www.news-medical.net/health/Gene-Expression-System.aspx [11.5.2012]"
    Nóta In the broadest sense this includes every living cell but the term is more normally used to refer to expression as a laboratory tool.An expression system is therefore often artificial in some manner. Expression systems are, however, a fundamentally natural process. Viruses are an excellent example where they replicate by using the host cell as an expression system for the viral proteins and genome.
    système d'expression | système d'expression génique | système d'expression génétique
    fr
    Sainmhíniú système basé sur un processus naturel, permettant de faire produire par une bactérie, un virus, une plante, une lignée cellulaire, un animal, une levure, etc., génétiquement modifié(e) à cet effet, une grande quantité d'une protéine d'intérêt qui ne lui appartient pas nécessairement (par ex. insuline) Tagairt Conseil-FR
  2. PRODUCTION, TECHNOLOGY AND RESEARCH|technology and technical regulations|biotechnology
    gunna géinte Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    gene gun | gene-gun
    en
    Sainmhíniú "apparatus used for biolistic transfections" Tagairt Gloss. of Rice Technology, 2001, IRRI
    canon à gènes | canon à particules | microcanon | pistolet à gènes | """fusil à gènes"""
    fr
    Sainmhíniú cylindre métallique fixe dans lequel est propulsé un macroprojectile recouvert de microbilles de tungstène enrobées d'ADN vers les cellules immobilisées d'un végétal afin d'obtenir par modifications génétiques des céréales transgéniques plus fertiles Tagairt Cahier de termes nouveaux,RINT,1992
  3. SCIENCE|natural and applied sciences|life sciences|biology · SCIENCE|natural and applied sciences|life sciences|biology|genetics
    ionduchtú géine Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Induktion
    de
    induction | gene induction
    en
    Sainmhíniú stimulated increase in the expression of a specific, target gene of a cellular organism Tagairt "COM-Terminology Coordination, based on: Bacteriophage Ecology Group. Induction (12.4.2021)"
    Nóta Most organisms are cellular organisms. Viruses, by contrast, do not consist of cells, and therefore are acellular.
    induction
    fr
    Sainmhíniú En virologie, ensemble des mécanismes cellulaires et moléculaires conduisant au déclenchement de l'expression d'un gène spécifique étudié chez les bactéries ou les levures. Tagairt ---
  4. SCIENCE|natural and applied sciences|life sciences|biology · PRODUCTION, TECHNOLOGY AND RESEARCH|technology and technical regulations|biotechnology
    inleagan géine Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    gene knock-in | gene KI
    en
    Sainmhíniú genetic engineering method that involves the one-for-one substitution of DNA sequence information in a genetic locus or the insertion of sequence information not found within the locus Tagairt "Wikipedia > Gene knock-in (13.4.2021)"
    Nóta "The difference between knock-in technology and traditional transgenic techniques is that a knock-in involves a gene inserted into a specific locus, and is thus a ""targeted"" insertion. It is the opposite of gene knockout. A common use of knock-in technology is for the creation of disease models. It is a technique by which scientific investigators may study the function of the regulatory machinery (e.g. promoters) that governs the expression of the natural gene being replaced. This is accomplished by observing the new phenotype of the organism in question."
    knock-in
    fr
  5. PRODUCTION, TECHNOLOGY AND RESEARCH|technology and technical regulations|biotechnology · SCIENCE|natural and applied sciences|life sciences|biology
    asleagan géine Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    asleagan Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    gene knock-out | gene knockout | knockout | gene knock out
    en
    Sainmhíniú "complete erasing of target genes, or inactivating them through nonsense mutations" Tagairt "Lakna. 'What is the Difference Between Gene Knockout and Knockdown' (26.1.2021). Pediaa"
    knock-out
    fr
  6. SCIENCE|natural and applied sciences|life sciences|biology · PRODUCTION, TECHNOLOGY AND RESEARCH|technology and technical regulations|biotechnology
    banc géinte Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Comhthéacs 'Ba é an Dr. Miguel Gorriz a chríochnaigh an banc géinte ar 208 crann fuinseoige a bhí fulangach do chríonadh siar na fuinseoige, agus seoladh 1,000 géinitíopa fuinseoige Éireannach thar lear dá scagthástáil faoi dhálaí diana brú galair. ' Tagairt "'Tuarascáil Bhliantúil 2019 agus na Ráitis Airgeadais,' Teagasc, https://www.teagasc.ie/media/website/publications/2020/Teagasc-Annual-Report-2019_Irish.pdf, [13.4.2022]"
    Gen-Biobliothek
    de
    gene library | gene bank
    en
    Sainmhíniú large collection of DNA fragments cloned from a given organism, tissue, organ, or cell type Tagairt "'gene library' (7.4.2021). MeSH"
    Nóta It may contain complete genomic sequences or complementary DNA sequences, the latter being formed from messenger RNA and lacking intron sequences.
    bibliothèque de gènes | génothèque | banque de gènes
    fr
    Sainmhíniú Ensemble de bactériophages hybrides contenant la totalité de l'information génétique du génome cellulaire.Ce peuvent être des banques d'ADNc ; en génétique classique, banque de génotypes conservés le plus souvent sous forme de gamètes ou d'embryons Tagairt BEP 83,p.118 ; arrêté du 14/09/90 relatif à la terminologie du génie génétique,JORF 26/09/90
  7. SCIENCE|natural and applied sciences|life sciences
    mapáil ghéiniteach Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Comhthéacs 'Áirítear iarrachtaí le seicheamh iomlán ADN orgánach a oibriú amach chomh maith le mapáil ghéiniteach ar an mionscála mar chuid de.' Tagairt "géanómaíocht'. Vicipéid. http://ga.wikipedia.org/wiki/G%C3%A9an%C3%B3ma%C3%ADocht [25.3.2015]"
    Aufstellung von Gen-Karten | Kartierung von Genomen | Genkartierung | genetische Kartierung
    de
    genetic mapping | gene mapping | genome mapping
    en
    Sainmhíniú assigning/locating of a specific gene to particular region of a chromosome and determining the location of and relative distances between genes on the chromosome Tagairt "National Center for Biotechnology Information, U.S. National Library of Medicine. Genome Mapping, http://www.ncbi.nlm.nih.gov/probe/docs/applmapping/ [31.10.2014]"
    Nóta "There are three types of maps:- linkage maps [ IATE:2211198 ]- physical maps [ IATE:1196421 ]- chromosome maps [ IATE:1625057 ]Some authors consider that genetic mapping is based on the use of genetic techniques to construct maps showing the positions of genes and other sequence features on a genome and therefore it constructs only linkage maps, and therefore they distinguish genetic mapping from physical mapping where molecular biology techniques to examine DNA molecules directly in order to construct maps showing the positions of sequence features, including genes.See also:- Brown TA. Genomes. Oxford: Wiley-Liss; 2002, http://www.ncbi.nlm.nih.gov/books/NBK21116/ [31.10.2014] - Lee M. Silver. Mouse Genetics. Concepts and Applications. 7.1 Genetic maps come in various forms. Mouse Genome Informatics, http://www.informatics.jax.org/silver/frames/frame7-1.shtml [31.10.2014]"
    construction de cartes génétiques | cartographie des génomes | établissement de cartes génétiques | cartographie de gènes | cartographie génétique | établissement de la carte factorielle
    fr
    Sainmhíniú Représentation de la localisation des gènes dans un génome. Tagairt ULB-Bio
  8. SCIENCE|natural and applied sciences|life sciences · PRODUCTION, TECHNOLOGY AND RESEARCH|technology and technical regulations|technology
    modhnú géine Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Genveränderung
    de
    gene modification
    en
    Sainmhíniú deletion, change, addition of a gene in an organism Tagairt "COM-EN, based on:Council for Responsible Genetics. POSITION PAPER ON HUMAN GERMLINE MANIPULATION http://www.councilforresponsiblegenetics.org/ViewPage.aspx?pageId=101 [9.3.2012]"
    modification génique | modification génétique
    fr
  9. SCIENCE|natural and applied sciences|life sciences
    sóchán géine Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    sóchán géinte Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Genmutation
    de
    Sainmhíniú Form der Mutation, die durch eine Änderung der Nukleotidsequenz der Gene entsteht Tagairt "Medizinlexikon > Genmutation, http://flexikon.doccheck.com/de/Genmutation (10.3.2017)"
    gene mutation
    en
    Sainmhíniú a genetic change at the level of the genes; a change in the nitrogenous base sequences Tagairt "Biology Online http://www.biology-online.org/dictionary/Gene_mutation [20.9.2010]"
    Nóta "Gene mutations may occur spontaneously during replication (called spontaneous mutations [ IATE:1254709 ]) or they may be induced through mutagens (called induced mutations).Gene mutations based on the mechanism that caused it are as follows:- base pair substitution [ IATE:1594439 ] - frame shift mutation Mutations [ IATE:1254707 ] are inherited or acquired. They can occur in a somatic cell (somatic cell mutation [ IATE:1096672 ] as well as in a germ cell (one that will give rise to gametes, i.e., egg or sperm cells). The change can be small, concerning one gene (gene mutation), or larger concerning more genes (chromosome mutation [ IATE:3524264 ]). Small changes may also concern the noncoding region of the genetic material (genetic mutation [ IATE:3524395 ]).Reference: COM-Terminology Coordination"
    mutation de gène | mutation génique | mutation de gènes
    fr
  10. SCIENCE|natural and applied sciences|life sciences|biology
    ionadú péire bunaidh Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Punktmutation
    de
    Sainmhíniú Deletion oder Insertion eines einzigen Basenpaares Tagairt Manfred Eichhorn, Langenscheidt-Redaktion (Hrsg.): Langenscheidt Fachwörterbuch Biologie Englisch-Deutsch. Langenscheidt: München, 2007, s. v. „point mutation“.
    gene point mutation | point mutation | mutations | substitution mutation | base pair substitution | substitutions
    en
    Sainmhíniú mutation in DNA or RNA molecule involving a change (replacement or substitution) of only one nucleotide base Tagairt "COM-EN, based on: Biology Online http://www.biology-online.org/dictionary/Base_pair_substitution & http://www.biology-online.org/dictionary/Point_mutation [20.9.2010]"
    Nóta "This type of mutation occurring in noncoding sequences often does not result in an altered amino acid sequence during translation. If a mutation in the promoter sequence of a gene occurs, the effect may be apparent since the expression of the gene may cause changes in the amino acid sequence, as well as the structure and function of the protein product.Point mutations may be classified on the basis of functionality:- nonsense mutation- missense mutation- silent mutation Depending on the type of nitrogenous base involved, this type of mutation may be categorized as:- transition- transversion Not to be confused with the broader term gene mutation [ IATE:1351106 ] which also covers frame shift mutation [ IATE:1687482 ]."
    mutation génique ponctuelle | mutation ponctuelle
    fr
    Sainmhíniú Mutation provoquée par la modification chimique d'un seul nucléotide(substitution d'une base à une autre). Tagairt Lehninger,p.869;JOF,14.3.86
  11. SCIENCE|natural and applied sciences|life sciences
    athchuingriú Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Rekombination | Genrekombination | Neukombination
    de
    recombination | genetic recombination | DNA recombination | gene recombination
    en
    Sainmhíniú "process by which two DNA molecules exchange genetic information, resulting in the production of a new combination of alleles11 allele [ IATE:1254616 ]" Tagairt "Wikipedia. Genetic recombination, http://en.wikipedia.org/wiki/Genetic_recombination [20.1.2014]"
    Nóta "In viruses, there are two types of recombination, self recombination and recombination with host.Self recombination occurs when two viral genomes recombine by homologous crossing over. This happens for DNA viruses and is very common in prokaryotic viruses, but also for RNA viruses or retroviruses. These recombination events can be of evolutionary advantage for the virus when it helps to evade host immune defenses, for example by changing surface protein antigenicity.Recombination with host or other organism occurs when a viral genome recombine to acquire sequences from another organism. Natural selection can retain acquired sequence if it gives an evolutionary advantage to the virus and mutations can modify its original functions. This event is common in large dsDNA viruses, some eukaryotic viruses even acquired many genes from bacteria.Reference: Viral genome evolution, http://viralzone.expasy.org/all_by_species/4136.html [11.7.2014]Not to be confused with:- genomic reassortment [ IATE:3561133 ]- genomic rearrangement [ IATE:1474160 ]."
    recombinaison | recombinaison génétique | recombinaison de l'ADN | recombinaison des gènes
    fr
    Sainmhíniú phénomène conduisant à l'apparition, dans une cellule ou dans un individu, de gènes ou de caractères héréditaires dans une association différente de celle observée chez les cellules ou individus parentaux Tagairt "Arrêté du 14 septembre 1990 relatif à la terminologie du génie génétique, http://www.legifrance.gouv.fr/affichTexte.do?cidTexte=LEGITEXT000006076553 [20.8.2014]"
  12. SCIENCE|natural and applied sciences|life sciences|biology|genetics · SCIENCE|natural and applied sciences|life sciences|biology
    rialú géine Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Gen-Regulierung | Genregulierung
    de
    gene regulation | gene control
    en
    Sainmhíniú "mechanism that acts to induce or repress the expression of a gene" Tagairt "'Gene regulation' (28.5.2020). Nature"
    Nóta These include structural and chemical changes to the genetic material, binding of proteins to specific DNA elements to regulate transcription, or mechanisms that modulate translation of mRNA.
    régulation génique | régulation génétique | régulation des gènes
    fr
  13. SCIENCE|natural and applied sciences · ENVIRONMENT|environmental policy|environmental policy · ENVIRONMENT|environmental policy|environmental protection
    caomhnú acmhainní géiniteacha Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Erhaltung genetischer Ressourcen
    de
    conservation of genetic resources | genetic resources conservation | gene resources conservation
    en
    Sainmhíniú the conservation of species, populations, individuals or parts of individuals, by in situ or ex situ methods, to provide a diversity of genetic materials for present and future generations Tagairt """gene resources conservation"", Food and agriculture organization of the United Nations. Glossary, http://www.fao.org/glossary/spec-term-n.asp?id_glo=3919&id_lang=TERMS_E [3.4.2013]"
    Nóta "See also: - in-situ conservation (narrower) [ IATE:3547625 - ex-situ conservation (narrower) [ IATE:1443500 ]"
    conservation des ressources génétiques
    fr
    Sainmhíniú conduite de l'utilisation humaine des ressources génétiques propre à procurer un maximum de bénéfices durables pour la génération actuelle tout en maintenant leur capacité de répondre aux besoins et aspirations des générations futures Tagairt "FAO, Conservation des ressources génétiques dans l'aménagement des forêts tropicales, http://www.fao.org/docrep/006/T0743F/T0743F00.HTM#glos [12.4.2013]"
  14. SCIENCE|natural and applied sciences|life sciences
    sochtadh géinte Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Gen-Silencing
    de
    Sainmhíniú „Inaktivierung von Genen [...], ohne dass sich der entsprechende DNA-Abschnitt verändert hat“ Tagairt "BMBF, http://www.biosicherheit.de/lexikon/680.gene-silencing.html [Stand: 23.6.2011]"
    gene silencing | silencing
    en
    Sainmhíniú interruption or suppression of the expression of a gene at transcriptional or translational levels Tagairt "'Gene silencing' (26.1.2021). lookfordiagnosis.com"
    Nóta "Some authors consider gene silencing the same as gene knockdown while others consider it as a broader term which encompasses gene knockdown and gene knockout."
    extinction de gènes | extinction de gène, extinction des gènes, extinction d'un gène | silence des gènes | extinction génique
    fr
    Sainmhíniú perte de l’expression génique, soit par altération de la séquence d’ADN d’un gène structural ou de sa région régulatrice, soit par des interactions entre son transcrit et autres ARNm présents dans la cellule Tagairt "Glossaire de la biotechnologie pour l’alimentation et l’agriculture, FAO, http://www.fao.org/glossary/spec-term-n.asp?id_glo=2326&id_lang=TERMS_F ou http://www.semencespaysannes.org/bdf/docs/glossaire_biotechnologie_fao.pdf [12.6.2012]"
    Nóta Chez certains organismes, l'ajout d'une copie supplémentaire d'un gène dans leur génome peut avoir un effet paradoxal et bloquer la production de la protéine qu'il code, au lieu de l'accentuer. (source: Biofutur, décembre 1999)
  15. PRODUCTION, TECHNOLOGY AND RESEARCH|technology and technical regulations|biotechnology|genetic engineering
    teagmhas cruachta Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    kombiniertes Transformationsereignis
    de
    gene stacked event | stacked transformation event | stacking of transformation events | GM stacked event | stacked event | stacked-gene transformation event
    en
    Sainmhíniú "genetic modification where more than one gene from another organism has been transferred and comprising more than one transformation event" Tagairt "COM-Terminology Coordination, based on:- Wikipedia > Gene stacked event (23.1.2023)- OECD. ENVIRONMENT DIRECTORATE JOINT MEETING OF THE CHEMICALS COMMITTEE AND THE WORKING PARTY ON CHEMICALS, PESTICIDES AND BIOTECHNOLOGY. Series on Harmonization of Regulatory Oversight in Biotechnology, No. 23 OECD GUIDANCE FOR THE DESIGNATION OF A UNIQUE IDENTIFIER FOR TRANSGENIC PLANTS (23.1.2023)- Regulation (EC) No 65/2004 establishing a system for the development and assignment of unique identifiers for genetically modified organisms"
    événement de transformation empilé | événements de transformation empilés | événement empilé | événements empilés
    fr
    Nóta "Voir aussi: - événement de transformation [IATE:929392 ] - événement de transformation simple[IATE:2203837 ]"
  16. PRODUCTION, TECHNOLOGY AND RESEARCH|technology and technical regulations|biotechnology
    innealtóireacht ghéiniteach Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Gentechnik | Gentechnologie | Genmanipulation | Gentechnikverfahren | genetische Manipulation
    de
    genetic engineering | gene technology | genetic manipulation
    en
    Sainmhíniú deliberate modification of the characteristics of an organism by manipulating its genetic material Tagairt "‘genetic engineering’. Oxford Dictionaries. Oxford University Press. http://www.oxforddictionaries.com/definition/english/genetic-engineering [4.12.2015]"
    technologie génétique | génie génétique | ingénierie génétique
    fr
    Sainmhíniú Ensemble de concepts, méthodes et techniques permettant de modifier le patrimoine héréditaire d'une cellule par la manipulation de gènes et/ou leur transfert. Le génie génétique permet ainsi de modifier, supprimer ou introduire certains caractères dans une cellule Tagairt ADEBIO,p.357
  17. SOCIAL QUESTIONS|health|medical science · PRODUCTION, TECHNOLOGY AND RESEARCH|research and intellectual property|research
    géinteiripe Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Gentherapie
    de
    gene therapy
    en
    Sainmhíniú experimental technique that uses genes to treat or prevent disease Tagairt "Genetics Home Reference. What is gene therapy? http://ghr.nlm.nih.gov/handbook/therapy/genetherapy [27.8.2014]"
    Nóta Researchers are testing several approaches to gene therapy, including: * replacing a mutated gene that causes disease with a healthy copy of the gene;* inactivating, or “knocking out,” a mutated gene that is functioning improperly;* introducing a new gene into the body to help fight a disease.Gene therapy is currently only being tested for the treatment of diseases that have no other cures.
    thérapie génétique | thérapie génique | traitement génique
    fr
    Sainmhíniú Traitement génétique des maladies héréditaires (p. ex. infection ex vivo de la moelle de malades par un rétrovirus porteur du gène manquant, puis regreffage de la moelle modifiée.). Tagairt Biofutur 10/85,p.28
  18. SOCIAL QUESTIONS|health|medical science · SOCIAL QUESTIONS|health|pharmaceutical industry
    táirge íocshláinte géinteiripe Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Gentherapeutikum
    de
    Sainmhíniú Arzneimittel, bei dem durch eine Reihe von Verarbeitungsgängen der (in vivo oder ex vivo erfolgende) Transfer eines prophylaktischen, diagnostischen oder therapeutischen Gens (d. h. eines Stücks Nukleinsäure) in menschliche oder tierische Zellen und dessen anschließende Expression in vivo bewirkt werden sollen Tagairt "Richtlinie 2003/63/EG der Kommission vom 25. Juni 2003 zur Änderung der Richtlinie 2001/83/EG des Europäischen Parlaments und des Rates zur Schaffung eines Gemeinschaftskodexes für Humanarzneimittel CELEX:32003L0063/DE"
    gene therapy medicinal product
    en
    Sainmhíniú biological medicinal product which has the following characteristics:(a) it contains an active substance which contains or consists of a recombinant nucleic acid used in or administered to human beings with a view to regulating, repairing, replacing, adding or deleting a genetic sequence;(b) its therapeutic, prophylactic or diagnostic effect relates directly to the recombinant nucleic acid sequence it contains, or to the product of genetic expression of this sequence. Tagairt "Directive 2001/83/EC on the Community code relating to medicinal products for human use"
    Nóta Gene therapy medicinal products shall not include vaccines against infectious diseases.
    médicament de thérapie génique
    fr
    Sainmhíniú tout produit obtenu par un ensemble de procédés de fabrication visant au transfert, in vivo ou ex vivo, d'un gène prophylactique, diagnostique ou thérapeutique (à savoir un morceau d'acide nucléique), vers des cellules humaines/animales et son expression consécutive in vivo Tagairt "Directive 2003/63/CE de la Commission, du 25 juin 2003, modifiant la directive 2001/83/CE du Parlement européen et du Conseil instituant un code communautaire relatif aux médicaments à usage humain , http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=CELEX:32003L0063:FR:HTML"
  19. SOCIAL QUESTIONS|health|pharmaceutical industry|veterinary medicinal product
    táirge íocshláinte tréidliachta géinteiripe Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    Comhthéacs '... maidir le táirgí teiripe frithbhríche RNA agus teiripe trasnaíochta RNA a bheartaítear don ghéinteiripe, cuirfear san áireamh na ceanglais maidir le táirge íocshláinte tréidliachta géinteiripe.' Tagairt "Rialachán Tarmligthe (AE) 2021/805 lena leasaítear Iarscríbhinn II a ghabhann le Rialachán (AE) 2019/6 ó Pharlaimint na hEorpa agus ón gComhairle, CELEX:32021R0805/GA"
    táirge géinteiripe Tagairt Faomhadh an téarma seo mar chuid de Thionscadal Lex
    ga
    gene therapy veterinary medicinal product | gene therapy product
    en
    Sainmhíniú "biological veterinary medicinal products that contain an active substance which contains or consists of a recombinant nucleic acid used in or administered to animals with a view to regulating, repairing, replacing, adding or deleting a genetic sequence and whose therapeutic, prophylactic or diagnostic effect relates directly to the recombinant nucleic acid sequence they contain, or to the product of genetic expression of this sequence" Tagairt "COM-Terminology Coordination, based on: Commission Delegated Regulation (EU) 2021/805 amending Annex II to Regulation (EU) 2019/6"